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令和4年度 
外国人留学生奨学金授与者

令和4年度 外国人留学生奨学金

受賞者
岳 海楠(がく かいなん)先生
順天堂大学大学院医学研究科 皮膚科学・アレルギー学講座
ご略歴
2015年 中国医科大学医学部臨床医学学科卒業
2017年 中国医科大学大学院修士課程修了(臨床医学研究科 神経学専攻)
2018年 順天堂大学大学院医学研究科 アトピー疾患研究センター研究生
2019年 順天堂大学大学院医学研究科 皮膚科学・アレルギー学講座博士過程入学
現在の研究テーマ
新規抗菌ペプチドであるAMP-IBP5による痒みの軽減効果とそのメカニズムの検討
論文発表
  • Yue H, Song P, Sutthammikorn N,Umehara Y,Trujillo-Paez JV, Nguyen HLT, Takahashi M,Peng G, Ikutama R, Okumura K, Ogawa H, Ikeda S, Niyonsaba F. Antimicrobial peptide derived from insulin-like growth factor-binding protein 5 improves diabetic wound healing. Wound Repair Regen. doi: 10.1111/wrr.12997, (in press, 2022)
  • Takahashi M, Umehara Y, Yue H, Trujillo-Paez JV, Peng G, Nguyen HLT, Ikutama R, Okumura K, Ogawa H, Ikeda S, Niyonsaba F. The antimicrobial peptide human β-defensin-3 accelerates wound healing by promoting angiogenesis, cell migration, and proliferation through the FGFR/」AK2/STAT3 signaling pathway. Front lmmunol. 12:712781, 2021, doi:10.3389/fimmu.2021.712781.
  • Sutthammikorn N, Supajatura V, Yue H, Takahashi M, Chansakaow S, Nakano N, Song P, Ogawa T, Ikeda S, Okumura K, Ogawa H, Niyonsaba F. Topical gynura procumbens as a novel therapeutic improves wound healing in diabetic mice. Plants. 10(6):1122, 2021. doi:10,3390/plants10061122.
  • Yue H, Umehara Y, Trujilllo-Paez JV, Peng G, Nguyen HLT, Chieosilapatham P, Kiatsurayanon C, Song P, Okumura K, Ogawa H, Ikeda S, Niyonsaba F. Exogenous factors in the pathogenesis of atopic dermatitis : irritants and cutaneous infection. Clin Exp Allergy. 51(3):382-392, 2021. doi: 10.1111/cea.13820.
  • Umehara Y, Kiatsurayanon C, Trujillo-Paez 」V, Chieosilapatham P, Peng G, Yue H, Nguyen HLT, Song P, Okumura K, Ogava H, Niyonsaba F. Intractable itch in atopic dermatitis: causes and treatments. Biomedicines. 9(3): 229, 2021. doi:10.3390/biomedicines9030229.
  • Chieosilapatham P, Kiatsurayanon C, Umehara Y, Trujillo-Paez JV, Peng G, Yue H, Nguyen LTH, Niyonsaba F. Keratinocytes: innate immune cells in atopic dermatitis, Clin Exp lmmunol. 204(3):296-309, 2021. doi: 10.1111/cei.13575.
  • Nguyen HLT, Trujillo-Paez JV, tlmehara Y, Yue H, Peng G, Kiatsurayanon C, Chieosilapatham P, Song P, Okuumura K, Ogawa H, Ikeda S, Niyonsaba F. Role of antimicrobial peptides in skin barrier repair in individuals with atopic dermatitis. Int 」 Mol Sci. 21(20): 7607, 2020. doi: 10.3390/ijms21207607.
  • Chieosilapatham P*, Yue H, Ikeda S, Ogawa H, Nityonsaba F. Involvement of the lipoprotein receptor LRP1 in AMP-IBP5-mediated migration and proliferation of human keratinocytes and fibroblasts. J Dermatol Sci. 99(3):158-167,2020. *contributed equally to this manuscript. doi:10.1016/j.jdermsci.2020.07.003.
  • Niyonsaba F, Song P, Yue H, Sutthammikorn N, Umehara Y, Okumura K, Ogawa H. Antimicrobial peptide derived from insulin-like growth factor-binding protein 5 activates mast cells via Mas-related G protein-coupled receptor X2. Allergy. 75(1):203-207, 2020. doi: 10.1111/all.13975.
学会発表
  • Yue H, Umehara Y, Nguyen HL, Takahashi M, Peng G, Ikutama R, Okumura K, Ogawa H, Ikeda S, Niyonsaba F. AMP-IBP5 improves diabetic wound healing via activation of EGFR/STAT/MAPK pathways. The 79th Annual Meeting of the Society for Investigative Dermatology. Chicago, May 2021.
  • Yue H, Umehara Y, Trujillo-Paez 」V, Peng G, Nguyen HL, Takahashi M, Ikutama R, Okumura K, Ikeda S, Ogawa H, Niyonsaba F. AMP-IBP5 improves diabetic wound healing via activation of EGFR/STAT pathway. The 120th Annual Meeting of the Japanese Dermatological Associationt Yokohama, June 2021.
  • Yue H, Umehara Y, Nguyen HL, Peng G, Takahashi M, Ikutama R, Okumura K, Ikeda S, Ogawa H, Niyonsaba F. Antimicrobial peptide derived from insulin-like growth factor-binding protein 5 improves diabetic wound healing via MAPK pathways. The 45th Annual Meeting of the Japanese Society for Investigative Dermatology, Nagoya, December 2020.
  • Takahashi M, Umehara Y, Yue H, Trujillo-Paez JV, Peng G, Nguyen HL, Ikutama R, Okumura K, Ogawa H, Ikeda S, Niyonsaba F. Effects of human β-defensin-3 on wound healing. The 45th Annual Meeting of the Japanese Society for Investigative Dermatology. Nagoya, December 2020.
  • Nguyen HL, Trujillo-Paez JV, Peng G, Yue H, Ikutama L, Takahashi M, Umehara Y, Ogawa H, Ikeda S, Niyonsaba F. The effect of antimicrobial peptide AMP-IBP5 on skin barrier regulation. The 45th Annual Meeting of the Japanese Society for Investigative Dermatology. Nagoya, December 2020.
  • Peng G, Ikutama R, Umehara Y, Trujillo V, Yue H, Nguyen HL, Takahashi M, Kakeyama S, Komatsu M, Okumura K, Ogawa H, Ikeda S, Niyonsaba F. Effect of hBD-3 on Th2 cytokine-mediated modulation of autophagy in human keratinocytes. The 45th Annual Meeting of the Japanese Society for Ilnvestigative Dermatology. Nagoya, December 2020.
  • Peng G, Kageyama S, Ikutama R, Umehara Y, Trujillo-Paez JV, Nguyen HL, Takahashi M, Yue H, Komatsu M, Okumura O, Ogawa H, Ikeda S, Niyonsaba F. Both human β-defensin-3 and autophagy are needed for maintenance of skin barrier. The 50th Annual Meeting of the Japanese Society for Cutaneous Immunology and Allergy. Kochi, December 2020.
  • Peng G, Kageyama S, Ikutama R, Umehara Y, Trujillo-Paez JV, Nguyen HL, Takahashi M, Yue H, Komatsu M, Okumura O, Ogawa H, Ikeda S, Niyonsaba F. The antimicrobial peptide human β-defensin-3 activates autophagy in human keratinocytes. The 78th Annual Meeting of the Society for Investigative Dermatology. 194.Scottsdale. Arizona, May 2020.
  • Yue H, Umehara Y, Trujillo-Paez 」V, Peng G, Okumura O, Ikeda S, Ogawa H, Niyonsaba F. Acceleration of diabetic wound healing by an antimicrobial peptide AVIP-IBP5. The 119th Annual Meeting of the Japanese Dermatological Association. Kyoto, June 2020.
  • Nguyen HL, Trujillo-Paez 」V, Peng G, Yue H, Ikutama R, Takahashi M, Umehara Y, Ikeda S, Ogawa H, Niyonsaba F. Effect of the antimicrobial peptide AMP-IBP5 on skin barrier regulation. The 119th Annual Meeting of the Japanese Dermatological Association. Kyoto,June 2020.
  • Yue H, Niyonsaba F, Umehara Y, Trujillo V, Okumura K, Ikeda S, Ogawa H. Effects of AMP-IBP5,an antimicrobial peptide derived from insulin-like growth factor-binding protein5 on diabetic wound healing. The 44th Annual Meeting of the Japanese Society for Investigative Dermatology. Aomori, November 2019.
  • Umehara Y, Sutthammikorn N, Song P, Yue H, Okumura K, Ogawa H, Niyonsaba F. Effects of antimicrobial peptide human β-defensin-3 on wound healing. The 44th Annual Meeting of the Japanese Society for Investigative Dermatology. Aomori, November 2019.